Metoprolol tartrate is a widely used medication that belongs to the beta-blocker class of drugs. It is commonly prescribed to manage high blood pressure, chest pain, and heart failure. Understanding the physical properties of metoprolol tartrate is crucial for pharmacists, researchers, and healthcare professionals.
Key features of metoprolol tartrate:
– Color: White to off-white
– Taste: Odorless
– Solubility: Soluble in water and ethanol
Explore the physical characteristics of metoprolol tartrate to enhance your knowledge of this important medication!
Chemical Structure and Formula
Metoprolol tartrate is a selective beta-1 adrenergic receptor blocker that exists in the form of a white, crystalline powder. Its chemical formula is C15H25NO3C4H6O6, and it has a molecular weight of 684.81 g/mol. The compound consists of metoprolol, a beta-blocker medication, combined with tartaric acid to form the tartrate salt, which enhances its solubility and bioavailability.
Chemical Structure and Formula
Metoprolol tartrate has a chemical formula C15H25NO3 and a molecular weight of 684.42 g/mol. The chemical structure of Metoprolol tartrate consists of a substituted benzene ring with a methylamino group and a hydroxyl group. The tartrate salt is formed by combining metoprolol with tartaric acid, resulting in a compound with improved water solubility and stability.
Physical Properties of Metoprolol Tartrate
Metoprolol tartrate is a crystalline powder that is white to off-white in color. It is odorless and has a slightly bitter taste. The melting point of Metoprolol tartrate is approximately 120-123°C.
Metoprolol tartrate is soluble in water, ethanol, and methanol. It has a molecular weight of 684.81 g/mol and a density of 1.0637 g/cm3 at 20°C.
- Appearance: Crystalline powder
- Color: White to off-white
- Taste: Slightly bitter
- Melting Point: 120-123°C
- Solubility: Soluble in water, ethanol, and methanol
- Molecular Weight: 684.81 g/mol
- Density: 1.0637 g/cm3 at 20°C
The physical properties of Metoprolol tartrate make it suitable for various pharmaceutical formulations and drug delivery systems.
Solubility and Stability
Metoprolol tartrate is a water-soluble beta-blocker that is widely used in the treatment of various cardiovascular conditions. It has good solubility in water, which allows for easy administration through oral and intravenous routes.
When it comes to stability, metoprolol tartrate is relatively stable under normal storage conditions. It is important to store the medication in a cool, dry place away from direct sunlight and moisture to maintain its potency and efficacy.
Overall, the solubility and stability of metoprolol tartrate make it a dependable choice for healthcare professionals in managing hypertension, angina, and other heart-related conditions.
Uses and Applications
Metoprolol tartrate is commonly prescribed for the treatment of:
- Hypertension (high blood pressure)
- Angina (chest pain)
- Heart failure
- Heart attacks
- Prevention of migraines
Metoprolol tartrate works by blocking the action of certain natural chemicals in the body, such as adrenaline, on the heart and blood vessels. This helps to lower blood pressure, reduce chest pain, and improve heart function.
It is important to follow your doctor’s instructions when taking metoprolol tartrate and not to stop abruptly as this can lead to serious health risks. Always consult with your healthcare provider for proper dosage and usage guidelines.
Comparison with Other Beta-Blockers
When compared to other beta-blockers, Metoprolol Tartrate stands out for its selective beta-1 receptor blocking properties. This selectivity allows for a more targeted approach to managing cardiovascular conditions while minimizing the risk of side effects associated with non-selective beta-blockers.
Additionally, Metoprolol Tartrate has a proven track record of efficacy and safety in treating various conditions such as hypertension, angina, and heart failure. Its rapid onset of action and relatively short half-life make it a preferred choice for acute situations where quick symptom relief is needed.
Compared to non-selective beta-blockers like propranolol, Metoprolol Tartrate is less likely to cause bronchoconstriction in patients with respiratory conditions such as asthma or COPD. This makes it a suitable option for patients with concomitant cardiovascular and respiratory issues.
In summary, Metoprolol Tartrate offers a unique combination of selectivity, efficacy, and safety that sets it apart from other beta-blockers in the management of cardiovascular diseases.